Welcome to Mid Game! You've unlocked the gloves, and you'll find it easier and easier to get back to that major CPS boost after ascensions. At this point, you're grinding out SP and paying attention to the Ascension Tree Tier List. There will be a few changes to gameplay mechanics, and you'll start setting yourself up for success in the Late Game.
Use this period to purchase a bulk of the Ascension Tree, through Tier 9. You'll start working on Minions, and increase your lifetime Slayer Points (SP). You’ll continue working through quests, likely finishing Expert Quests and preparing for Master Quests in the late game.
A word about minions: at first, they’ll seem like a waste of time and a cause of frustration, as they’ll need you to regularly ascend to gain the SP necessary to spend on their quests. But, as you’ll see, they’re an important element of this stage and set you up for success in the next stage.
During this stage, you'll have just unlocked the use of your Bow. At first, this will seem novel. But once you unlock Stability and Triple Shot in the tree, you’ll find that game mechanics have significantly changed. In addition, there are upgrades which specifically generate more soul gain from Bow kills, which means you’ll want to kill as many enemies with the Bow as possible.
Equipment - After your first few ascensions after the Gloves, you’ll be able to return to glove level quickly and you’ll be able to upgrade all items rapidly. Work to collect all achievements tied to equipment leveling, as this will help boost your CPS.
As you follow the Tier List to unlock ascension skills, you’ll soon unlock the Sacred Book of Projectiles and enable use of your bow. At this point, leveling your bow aggressively becomes important as there are helpful upgrades related to bow level. Don't hesitate to save and unlock Stability and Trip Shot sooner than later.
Quests: Continue working the quests. Nothing is overwhelming yet at this stage, so stay in specific zones to finish quests before moving on. If you’re looking for a place to focus, pay attention to enemy evolutions who pay quick dividends.
Portals: You’ll want to use portals to complete quests, but you’ll also want to actively stay in specific locations for longer, in order to maximize SP gathering. Once unlocking Mystic Valley and Enchanted Arrows, it’ll become a slightly better zone for SP farming for a while. Haunted Mansion continues to be a good option as well! By the time you complete the Expert Quests near the end of this time (or perhaps in the next stage), you’ll have most enemy evolutions unlocked. Hills will become the best zone for farming SP until you unlock the Factory.
Minions: You’ll have started working on Minions at this point. You should actively invest as much SP into your Minions as possible. At first, it’ll seem like you’re ‘wasting’ SP. But in fact, you’re investing in both SP and CPS gain as well as Divinity Points, which you’ll unlock in the next stage of the game and which you earn based on Minion levels. As soon as you unlock Divinities, you’ll want to have as many minion levels earned as possible. At this stage, the White Knight, Dark Wizard, Stone Golem and possibly even the Skeleton will begin to turn a decent, sustainable source of SP. This is a definite focus for this section.